PLAYING A ROLE IN PROTEIN PRODUCTION!
ESTIMATED TIME TO COMPLETE: 90 minutes
CONCEPT(S) LEARNED IN THIS MODULE:
- Students will be able to describe the process of transcription, including the definition of codon.
- Students will be able to describe translation as mRNA into amino acid sequences.
STANDARDS ADDRESSED IN THIS UNIT MODULE (AAAS PROJECT 2061):
- DNA is transcribed into mRNA in the nucleus. The single stranded mRNA molecule has slightly different base-pairing rules than DNA (U-T, C-G). When mRNA leaves the nucleus it travels into the cytoplasm to find a free ribosome where translation occurs. mRNA is translated into a string of amino acids.
- Protein molecules are long, usually folded chains made from 20 different kinds of amino-acid molecules (5C, Grades 9-12, 3).
- The genetic information encoded in DNA molecules provides instructions for assembling protein molecules (5C, Grades 9-12, 4).
TECHNOLOGY-ENHANCED INSTRUCTIONAL STRATEGIES UTILIZED IN THIS MODULE:
||Brief Description of Module
|Materials / Technology
||Given a sequence of DNA, can we make a protein? Model - Teacher
involves students in the process of transcription and translation by assigning roles (nucleus, ribosomes, cytoplasm, DNA, mRNA, tRNA, etc.)
||Inside the Cell - the classroom is set up like a cell. Students will navigate around the cell (classroom) to transcribe and translate DNA into a protein. The end product will be a sentence which will represent a protein.
||Central Dogma (DNA-RNA-protein)*the explanation of transcription and translation may better serve the students if it appears before the exploration.
||Waksman: Brain Drain Challenge 2Protein Sequence and Function.
||Internet Access- Rutgers
||Students will be evaluated on translating the given DNA sequence from the Waksman Challenge into an amino acid sequence. Students will deduce the function of this protein by relying on the skills they built by using the genetic databases in module 2.
||Internet Access - BLAST Rutgers
EXPECTED MODULE OUTCOMES:
PERFORMANCE-BASED ASSESSMENT OF MODULE OUTCOMES:
- Students will be able to transcribe and translate a sequence of DNA into a protein. By navigating through the cell (classroom), students will match the organelle with the location of the particular process of transcription and translation.
- Students will discuss how they translated the DNA sequence, posed by the Waksman Challenge, into an amino acid sequence.
- Students will propose what the function of the protein is by conducting teleresearch using databases and other web-based tools of choice.